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Chopin's Catarrh cf2 - canon mensurabilis (Cystic Fibrosis CFTR 508delF mutation)

from Peter Gena: Beethoven in Soho and Other Works by Peter Gena

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about

"Chopin’s Catarrh (Nocturnes)" was the first of Gena’s DNA-derived compositions to use acoustic instruments — Disklaviers, or computer-driven pianos. Dr. Strom informed Gena that Frédéric Chopin’s symptoms and physical characteristics suggest that he more likely suffered from cystic fibrosis rather than (or in addition to) the consumption that was long considered his fatal malady. Gena, immediately inspired by the Chopin connection to write for piano(s), transformed the DNA sequence for cystic fibrosis into musical notation, and then searched through Chopin’s nocturnes for note patterns that matched the DNA cantus firmus. These passages were then woven into the work. The first version, for one piano, was written in 2005. The present version, titled Chopin’s Catarrh cf2—canon mensurabilis, was finalized in 2023. (“cf2”stands for “cystic fibrosis cantus firmus.”) As the title indicates, it is a canon, one piano playing the other piano’s notes at different speeds. Within the texture one can hear
one piano’s notes echoing the other’s at increasing distance.

credits

from Peter Gena: Beethoven in Soho and Other Works, released October 6, 2023
two computer-driven pianos; DNA Consultation: Charles M. Strom PhD, MD

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